Cell specific dopamine modulation of the transient potassium current in the pyloric network by 1 the canonical D 1 receptor signal transduction cascade 2 3
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چکیده
Cell specific dopamine modulation of the transient potassium current in the pyloric network by 1 the canonical D1 receptor signal transduction cascade 2 3 Hongmei Zhang, Edmund W. Rodgers, Wulf-Dieter C. Krenz, Merry C. Clark, Deborah J. Baro 4 Department of Biology, Georgia State University, Atlanta, Georgia 30303 5 6 7 8 Running Head: D1 receptor signaling in the pyloric circuit 9 10 11 12 13 Contact Information: 14 Deborah J. Baro 15 Department of Biology 16 Georgia State University 17 P.O. Box 4010 18 Atlanta GA 30302-4010 19 Tel: (404) 413 5310 20 Fax: (404) 413 5301 21 [email protected] 22 23 24
منابع مشابه
Cell specific dopamine modulation of the transient potassium current in the pyloric network by the canonical D1 receptor signal transduction cascade.
Dopamine (DA) modifies the motor pattern generated by the pyloric network in the stomatogastric ganglion (STG) of the spiny lobster, Panulirus interruptus, by directly acting on each of the circuit neurons. The 14 pyloric neurons fall into six cell types, and DA actions are cell type specific. The transient potassium current mediated by shal channels (I(A)) is a common target of DA modulation i...
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The two pyloric dilator (PD) neurons are components [along with the anterior burster (AB) neuron] of the pacemaker group of the pyloric network in the stomatogastric ganglion of the spiny lobster Panulirus interruptus. Dopamine (DA) modifies the motor pattern generated by the pyloric network, in part by exciting or inhibiting different neurons. DA inhibits the PD neuron by hyperpolarizing it an...
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